Gene interactions and pathways from curated databases and text-mining

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APOB — ITGAM

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Han et al., J Lipid Res 2003 : LDL induced the expression of the monocyte CD11b in vitro as well as in vivo via intracellular signaling mechanisms involving calcium transients ... Neither oxidized LDL nor HDL had any effect on CD11b expression ... Although LDL stimulated CD11b surface expression, the integrins were not activated
Palvinskaya et al., Pulm Pharmacol Ther 2013 (Hypercholesterolemia...) : Paradoxically, LDL oxidation yielded the opposite effect on LDL induced CD11b display and actin polymerization, and both native and oxidized LDL were found to induce neutrophil transcription of the monocyte chemoattractant MCP-1
Rovers et al., Atherosclerosis 1998 (Hyperlipoproteinemia Type II) : In addition, LDL-apheresis inhibited IL-1 and TNF production and the expression of CD11a, CD11b , CD11c and CD14 by the mononuclear cells of FH patients and this may be an additional beneficial effect of LDL-apheresis apart of decreasing LDL concentrations