Gene interactions and pathways from curated databases and text-mining

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APOB — IL10

Text-mined interactions from Literome

Sasaki et al., Biol Pharm Bull 1999 : The effects of interleukin (IL)-4 and IL-10 on macrophage growth stimulating activities of oxidized low density lipoprotein (LDL), acetylated LDL and macrophage colony stimulating factor : the activity of oxidized LDL is refractory to the inhibitory cytokines ... To learn further the physiological regulation of macrophage growth, we comparatively examined the effect of interleukin (IL)-4 and IL-10 which have been reported to be suppressive to various macrophage functions on macrophage growth stimulating activities of the acetyl-LDL, oxidized LDL and macrophage colony stimulating factor ( M-CSF ) ... The growth inducing activity of acetyl-LDL was significantly inhibited by both IL-4 and IL-10 ... On the other hand, the activity of oxidized LDL was not attenuated by IL-4 or IL-10
Varadhachary et al., Cell Immunol 2001 : We demonstrate that LDL , upon binding to its receptor, induces interleukin (IL)-10 production from macrophages and biases naive T cells to become Th2-like
Tapiero et al., Biomed Pharmacother 2004 (Cardiovascular Diseases...) : In addition, Ox-LDL enhances the production and release of tumor necrosis factor ( TNF-alpha ), interleukin (IL)-6, arachidonic acid metabolites and nitric oxide ( NO ) that are responsible for various human pathologies including cancer
Hakala et al., Arterioscler Thromb Vasc Biol 2006 (Inflammation) : Using cytokine cDNA arrays, we found that H-LDL induced expression of IL-8, but not of the anti-inflammatory cytokines IL-10 and transforming growth factor ( TGF ) -beta, in human monocyte derived macrophages