Peng et al., Life Sci 2010
:
The results showed that both IL-6 and Ang II increased CRP levels in the supernatant of VSMCs and induced mRNA and protein expression of CRP in VSMCs, whereas pretreatment of the cells with EGCG ( 1 x 10 ( -6 ) M, 3 x 10 ( -6 ) M, 10 x 10 ( -6 ) M ) significantly inhibited IL-6- and Ang II-induced production and expression of CRP in VSMCs in a concentration dependent manner
Ortiz et al., Journal of the American Society of Hypertension : JASH 2009
:
Ang II-infusion increased plasma CRP from 14 +/- 2 to 26 +/- 3 mug/mL and increased urinary CRP excretion nearly 8-fold ( 143 +/- 26 vs 1102 +/- 115 ng/d )
Li et al., Cell Physiol Biochem 2011
(MAP Kinase Signaling System) :
Although angiotensin II (Ang II) can stimulate the vascular cells to produce CRP, it is unknown whether Ang II induces CRP expression in macrophages