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HOXA9 — TPO
Text-mined interactions from Literome
Kirito et al., Mol Cell Biol 2004
(MAP Kinase Signaling System) :
To extend our studies, we investigated the
effects of
TPO on
HOXA9 in this same cell population ... Although overall levels of the transcription factor were not affected, we found that
TPO induced the nuclear import of
HOXA9 both in UT-7/TPO cells and in primitive Sca-1 ( + ) /c-kit ( + ) /Gr-1 ( - ) hematopoietic cells in a mitogen activated protein kinase dependent fashion
Kaushansky et al., Ann N Y Acad Sci 2005
:
We found that
TPO enhances the transcription of HoxB4,
induces the nuclear localization of
HoxA9 , and upregulates VEGF expression by reducing the ubiquination of hypoxia inducible factor