◀ Back to SP1
CAV1 — SP1
Text-mined interactions from Literome
Bist et al., Biochemistry 2000
:
Okadaic acid, previously shown to inhibit growth, FC efflux, and
caveolin expression,
inhibited E2F/Sp1 binding, while higher concentrations of extracellular FC increased it
Dasari et al., Cancer Res 2006
:
In addition, signaling studies show p38 mitogen activated protein kinase ( MAPK ) as the upstream regulator of
Sp1 mediated activation of the
caveolin-1 promoter following oxidative stress ... Inhibition of p38 MAPK prevents the oxidant induced
Sp1 mediated up-regulation of
caveolin-1 protein expression and development of premature senescence