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AHR — SP1

Pathways - manually collected, often from reviews:

• FastForward regulation: SP1 → AHR (transcriptional regulation, unknown)
  Evidence: DNABINDING

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: AHR — SP1 (direct interaction, pull down) Wang et al., Biochemistry 1999*
• IRef Hprd Interaction: Complex of ARNT-SP1-AHR-SP1-AHR-ARNT-AHR-SP1-ARNT (in vivo) Wang et al., Biochemistry 1999*
• IRef Ophid Interaction: AHR — SP1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Racky et al., Arch Biochem Biophys 2004 : The obtained results prove an involvement of Sp1 in AhR gene regulation
Tang et al., Free Radic Biol Med 2010 : The objective of this study was to investigate the regulatory role of specificity protein-1 (Sp1) in AhR expression in MAECs that overexpress Cu/Zn-SOD and/or catalase