Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
NRAS
→
SOS1
(directlyIncreases, SOS1 Activity, NRAS Activity)
Zhao et al., Nat Cell Biol 2007* Evidence: The activation of Ras by the guanine nucleotide-exchange factor Son of sevenless (Sos) constitutes the rate-limiting step in the transduction process that links receptor tyrosine kinases to Ras-triggered intracellular signalling pathways.
KEGG Gap junction:
SOS1/SOS2
→
HRAS/KRAS/NRAS
(protein-protein, activation)