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MAPK3 — MST1

Text-mined interactions from Literome

Danilkovitch et al., Mol Cell Biol 2000 (MAP Kinase Signaling System) : Despite activation of MAPK by MSP , anoikis was not prevented in suspended cells with a blocked PI3-K/AKT pathway
Thomas et al., Cancer Res 2007 (Disease Progression...) : Finally, HGFL stimulation of pancreatic cancer cells resulted in increased expression of phospho-mitogen activated protein kinase and phospho-Akt
Ma et al., Int J Oncol 2010 (Neoplasms) : In colon and pancreatic cancer cells, RONDelta85 inhibits spontaneous or MSP induced Erk1/2 and AKT phosphorylation, which results in impaired cell proliferation and colony formation
Xiangming et al., Braz J Med Biol Res 2011 (MAP Kinase Signaling System) : Stimulation of RE7 cells with MSP resulted in increased migration ( about 69 % of the wounded areas were covered ) as well as increased activation of extracellular signal regulated kinase 1/2 ( Erk1/2 ) and glycogen synthase kinase-3ß ( GSK-3ß ; the percent of the activation ratio was 143.6/599.8 % and 512.4 %, respectively ), which could be inhibited with an individual chemical inhibitor PD98059 ( 50 µM ) specific to MAPK/ERK kinase ( the percent inhibition was 98.9 and 81.2 %, respectively )
Lee et al., Eur J Pharmacol 2013 : Increased protein expression of phospho-p38 MAPK was attenuated by MSP , while phospho-extracellular signal regulated kinase and c-Jun-N-terminal kinase were not affected
Creasy et al., J Biol Chem 1995 : MST1 activity decreases approximately 2-fold upon treatment with epidermal growth factor ; however, overexpression of MST1 does not affect extracellular signal regulated kinase-1 and -2 activation
Graves et al., EMBO J 1998 : Mst1 activates MKK6, p38 MAPK , MKK7 and SAPK in co-transfection assays, suggesting that Mst1 may activate these pathways