Gene interactions and pathways from curated databases and text-mining

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JUN — TRAF1

Text-mined interactions from Literome

Lee et al., J Biochem Mol Biol 2002 : The AP1 activation by TRAF2, TRAF5 , and TRAF6 was also greatly suppressed by the dominant negative TAK1
Bryce et al., Int Immunol 2006 (Hypersensitivity...) : We have previously reported that tumor necrosis factor receptor associated factor 1 ( TRAF1 ), an intracellular protein, which binds to a range of molecules, including tumor necrosis factor (TNF) receptor family members, regulates TNF induced NF-kappaB and AP-1 signaling as well as TCR triggered proliferative responses in T cells
Blackwell et al., Mol Cell Biol 2009 (Lymphoma) : Notably, TRAF2 phosphorylation increased both basal and inducible c-Jun and NF-kappaB activities and rendered cells resistant to stress induced apoptosis