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JUN — TRAF1
Text-mined interactions from Literome
Lee et al., J Biochem Mol Biol 2002
:
The
AP1 activation by TRAF2,
TRAF5 , and TRAF6 was also greatly suppressed by the dominant negative TAK1
Bryce et al., Int Immunol 2006
(Hypersensitivity...) :
We have previously reported that tumor necrosis factor receptor associated factor 1 (
TRAF1 ), an intracellular protein, which binds to a range of molecules, including tumor necrosis factor (TNF) receptor family members,
regulates TNF induced NF-kappaB and
AP-1 signaling as well as TCR triggered proliferative responses in T cells
Blackwell et al., Mol Cell Biol 2009
(Lymphoma) :
Notably,
TRAF2 phosphorylation
increased both basal and inducible
c-Jun and NF-kappaB activities and rendered cells resistant to stress induced apoptosis