Gene interactions and pathways from curated databases and text-mining

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JUN — TGFB2

Text-mined interactions from Literome

Wong et al., Mol Cell Biol 1999 : Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta
Seppänen et al., Oncol Res 1998 (Adenocarcinoma...) : In the present study, we have investigated the effects of interferons-alpha (IFN-alpha) and -gamma ( IFN-gamma ), interleukin-10 (IL-10) and -13 ( IL-13 ), transforming growth factor-beta1 ( TGF-beta1 ), granulocyte-macrophage colony stimulating factor ( GM-CSF ), and tumor necrosis factor-alpha (TNF-alpha) on cell proliferation and induction of transcription factors AP-1 and NF-kappaB in UM-EC-3 human endometrial adenocarcinoma cells and UT-OC-5 ovarian carcinoma cells in vitro
Dennler et al., J Biol Chem 2000 : c-Jun inhibits transforming growth factor beta mediated transcription by repressing Smad3 transcriptional activity
Wang et al., Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2001 : Heat shock induces elevated expression of hsp, c-Jun , CLK-1 gene while decreases expression of integrin alpha-4 and transforming growth factor beta
Matsuzaki et al., Hepatology 2007 (Carcinoma, Hepatocellular...) : Conversely, transforming growth factor beta ( TGF-beta ) activates not only TGF-beta type I receptor ( TbetaRI ) but also c-Jun N-terminal kinase (JNK) , which convert the mediator Smad3 into two distinctive phosphoisoforms : C-terminally phosphorylated Smad3 ( pSmad3C ) and linker phosphorylated Smad3 ( pSmad3L )
Markovics et al., J Biol Chem 2010 (Inflammation) : Transcription of the transforming growth factor beta activating integrin beta8 subunit is regulated by SP3, AP-1 , and the p38 pathway