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Text-mined interactions from Literome

Leonardi et al., J Biol Chem 2000 : TRAF2 is required for TNF induced activation of c-Jun N-terminal kinase/stress activated protein kinase ( JNK/SAPK ), and TRAF2 can also mediate activation of NF-kappaB
Li et al., Nature 2002 : TRAF2 is required for TNF-alpha mediated activation of c-Jun N-terminal kinase (JNK) , contributes to activation of NF-kappaB, and mediates anti-apoptotic signals,
Lee et al., J Biochem Mol Biol 2002 : The AP1 activation by TRAF2 , TRAF5, and TRAF6 was also greatly suppressed by the dominant negative TAK1
Park et al., J Biol Chem 2003 (Hepatitis C) : Because TRAF2 is required for the activation of both NF-kappaB and c-Jun N-terminal kinase (JNK) , we investigated HCV NS5A protein for its potential capacity to modulate TRAF2 mediated JNK activity
Ishizawa et al., Biol Cell 2006 : xFADD and xRIP1 synergistically induced the activation of AP-1 and NF-kappaB, both of which were partially mediated by TRAF2 ( tumour-necrosis-factor-receptor associated factor 2 ) and TAK1 ( transforming-growth-factor-beta activated kinase 1 )
Blackwell et al., Mol Cell Biol 2009 (Lymphoma) : Notably, TRAF2 phosphorylation increased both basal and inducible c-Jun and NF-kappaB activities and rendered cells resistant to stress induced apoptosis
Lee et al., J Cell Physiol 2010 (MAP Kinase Signaling System) : Taken together, these data suggest that in A549 cells, TNF-alpha induces MMP-9 expression via the TNFR1/TRAF2/PKCalpha dependent JNK1/2/c-Jun and c-Src/EGFR/PI3K/Akt pathways
Zhang et al., Mol Biol Cell 2011 : Tumor necrosis factor a (TNF-a) receptor associated factor 2 ( TRAF2 ) regulates activation of the c-Jun N-terminal kinase (JNK)/c-Jun and the inhibitor of ?B kinase ( IKK ) /nuclear factor ?B ( NF-?B ) signaling cascades in response to TNF-a stimulation