Gene interactions and pathways from curated databases and text-mining

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E2F1 — JUN

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Dong et al., Tumour Biol 2007 (Melanoma) : E2F-1 overexpression resulted in the transient activation of c-Jun N-terminal kinase (JNK) ; however, dominant negative mutant ASK1 had no effect on E2F-1 cytotoxicity and JNK activation
Shen et al., Oncogene 2008 (Breast Neoplasms) : AP-1 blockade also led to reduced expression of E2F1 and E2F2, but not E2F4, at the mRNA and protein levels