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IRF6 — TCF3
Text-mined interactions from Literome
Steer et al., J Biol Chem 2000
:
LPS increased nuclear c-Jun/ATF-2, NF-kappaB ( 1 ) /Rel-A, and Rel-A/C-Rel
transcription factor complexes, which bound specifically to oligonucleotide sequences from the -106 to -88 base pair ( bp ) region of the promoter
Medvedev et al., J Immunol 2000
(MAP Kinase Signaling System) :
In this study, the effect of in vitro endotoxin tolerance on
LPS induced mitogen activated protein kinase activation,
transcription factor induction , and cytokine, chemokine, and Toll-like receptor (TLR) 2 and 4 gene expression, as well as the involvement of TNF and IL-1 signaling pathways in tolerance, were examined
Heiss et al., J Biol Chem 2001
:
Consequently, nuclear factor kappa B (NF-kappa B), a pivotal
transcription factor in
LPS stimulated pro-inflammatory response, was identified as the key mediator
Hullinger et al., J Biol Chem 2001
:
5'-Deletion analysis and gel shift data suggest that
LPS inhibits binding of a novel
transcription factor to a myeloid zing finger protein-1-like element ( -476 to -456 ) in the human SR-BI promoter
You et al., Biochem Biophys Res Commun 2002
:
Transient expression and electrophoretic mobility shift assays with NF-kappaB binding sites revealed that NP reduced the levels of the
LPS induced NF-kappaB
transcription factor complex
Gordon et al., J Immunol 2003
:
We have found that the binding of the
transcription factor , Yin Yang 1 (YY1), to hs3 and to the mu E1 site of the intronic enhancer, E mu, is induced in primary splenic B cells after approximately 48 h in
response to
LPS and other activators of class switch recombination
Kim et al., Cancer Lett 2003
:
Transient expression and electrophoretic mobility shift assays with NF-kappaB binding sites revealed that BPA reduced the levels of the
LPS induced NF-kappaB
transcription factor complex
Sarkar et al., FEBS Lett 2003
(Inflammation) :
alpha-MSH also inhibited
SA-LPS induced nuclear
transcription factor kappaB activation not only in macrophages, but also in a T-cell line and human neutrophils isolated from fresh blood
Tang et al., Proc Natl Acad Sci U S A 2005
:
LPS induces the interaction of a
transcription factor , LPS induced TNF-alpha factor, and STAT6 ( B ) with effects on multiple cytokines
Equils et al., Clin Exp Immunol 2006
:
Here we show that 1,25- ( OH ) 2 D3 pretreatment of human microvessel endothelial cells ( HMEC ) inhibited the enteric gram negative bacterial
lipopolysaccharide (LPS) activation of
transcription factor NF-kappaB and interleukin (IL)-6, IL-8 and regulated upon activation normal T cell exposed and secreted ( RANTES ) release
Djoko et al., J Agric Food Chem 2007
(Inflammation) :
In further, when these stilbenoids were subjected to monitoring their inhibitory effectiveness on
LPS induced
transcription factor expressions of C/EBPdelta and C/EBPbeta, only C/EBPdelta expressions were reduced
Shembade et al., EMBO J 2007
:
The NF-kappaB
transcription factor is normally transiently
activated by proinflammatory cytokines and bacterial
lipopolysaccharide (LPS) ; however, persistent NF-kappaB activation is commonly observed in inflammatory disease and malignancy
Uchida et al., J Surg Res 2008
(Disease Models, Animal...) :
NE inhibitor prevented the activation of the
transcription factor , nuclear factor-kappa B,
induced by
GalN/LPS
Aoki et al., Biol Pharm Bull 2008
:
To determine the role of nitric oxide ( NO ) in rat liver transporter regulation, we investigated whether NO mediates
lipopolysaccharide (LPS) induced changes in transporters and their
transcription factor expression using aminoguanidine ( AG ), an inhibitor of induced nitric oxide synthase (iNOS)
Radnai et al., J Nutr 2009
(Inflammation) :
Additionally, FA inhibited
LPS induced activation of nuclear factor kappaB
transcription factor in the liver of the mice
Chang et al., J Pharmacol Sci 2009
:
Furthermore, the
LPS induced degradation of cytosolic IkappaB-alpha and activation of nuclear
transcription factor-kappaB ( NF-kappaB ) were also inhibited by FC-77
Haschemi et al., PloS one 2011
(Inflammation) :
Previously, we demonstrated that CO inhibits
lipopolysaccharide (LPS) induced expression of the proinflammatory early growth response-1 (Egr-1)
transcription factor in macrophages via activation of PPAR?
Vilekar et al., Int Immunol 2012
:
These effects were accompanied by the inhibition of
LPS induced activation of
transcription factor nuclear factor kappa-light-chain enhancer of activated B cells ( NF-?B )
Li et al., Inflamm Res 2013
(Mastitis) :
Further studies revealed that salidroside down-regulated phosphorylation of
LPS induced nuclear
transcription factor-kappaB ( NF-?B ) p65 and inhibitor of NF-?B a ( I?Ba ) in the NF-?B signal pathway, and suppressed phosphorylation of p38, extracellular signal regulated kinase ( ERK ) and c-jun NH ( 2 ) -terminal kinase ( JNK ) in MAPKs signal pathways
Smith et al., PLoS Pathog 2012
(Malaria) :
Here we report on the involvement of the Anopheles gambiae orthologue of a conserved component of the vertebrate immune system,
LPS induced TNFa
transcription factor ( LITAF ), and its role in mosquito anti-Plasmodium immunity
Wu et al., Int J Immunopathol Pharmacol 2012
(Liver Failure, Acute) :
In addition, pretreatment mice with PD dose-dependently suppressed tumor necrosis factor-alpha (TNF-alpha) production, myeloperoxidase (MPO) activity, intercellular adhesion molecule-1 ( ICAM-1 ) and endothelial cell adhesion molecule-1 ( ECAM-1 ) expression, caspase-3 activation, and
transcription factor nuclear factor-kappa B(NF-kB) activity
induced by
LPS
Büscher et al., Mol Cell Biol 1995
:
Both CSF-1 and
LPS rapidly activate the MAPK network and
induce the phosphorylation of two distinct ternary complex factors ( TCFs ),
TCF/Elk and TCF/SAP
Hu et al., J Biol Chem 1998
:
To ascertain how P2Z/P2X7 receptor antagonists influence LPS signaling, we evaluated the capacity of o-ATP to regulate
LPS mediated activation of the
transcription factor , nuclear factor-kappaB, and the mitogen activated protein kinases, extracellular signal regulated kinase ( ERK ) 1 and ERK2
Rescigno et al., J Exp Med 1998
:
We found that
LPS induced nuclear translocation of the nuclear factor (NF)-kappaB
transcription factor