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IRF6 — SYK
Text-mined interactions from Literome
Arndt et al., J Biol Chem 2004
:
In addition,
LPS stimulation of non suspended neutrophils
activates Syk and phosphatidylinositol 3-kinase (PI3K) ... Furthermore we show that PI3K inhibition decreased
LPS induced
Syk activation suggesting that PI3K resides upstream of Syk in this pathway
Ulanova et al., J Endotoxin Res 2007
:
We hypothesized that
Syk is involved in inflammatory responses
induced by the
lipopolysaccharide (LPS)
Lu et al., PLoS Pathog 2012
(Inflammation...) :
We found that
LPS treated neutrophils
induced phosphorylation of
Syk resulting in the formation of a complex including TLR4, p-Syk, and p-CEACAM1, which in turn, recruited the inhibitory phosphatase SHP-1
Zhu et al., Int Immunopharmacol 2013
(Disease Models, Animal...) :
These findings demonstrated that ß-glucan activation of
Dectin1/Syk attenuated
LPS induction of TLR4/MyD88/NF-?B and inhibited the LPS induced inflammation factors in mammary epithelial cells, thereby providing a possibly protective effect of ß-glucan in the prevention of LPS induced dysfunction in mammary epithelial cells