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IRF6 — MAP2K1

Text-mined interactions from Literome

Dumitru et al., Cell 2000 (MAP Kinase Signaling System...) : LPS stimulation of peritoneal macrophages from these mice did not activate MEK1 , ERK1, and ERK2 but did activate JNK, p38 MAPK, and NF-kappaB
Stollenwerk et al., Atherosclerosis 2005 (Arteriosclerosis...) : VLDL activated mitogen activated protein kinase-ERK kinase 1/2 ( MEK1/2 ), and potentiated LPS induced MEK1/2 activation
Minami et al., J Biol Chem 2008 (Atherosclerosis) : Similarly, directed EPRAP expression in RAW264.7 cells suppresses LPS induced p105 phosphorylation and degradation, and subsequent activation of mitogen activated protein kinase kinase 1/2
Tsai et al., Inflammation 2008 : Furthermore, ATRA suppressed the expression of LPS stimulated c-Raf, MKK1/2 and ERK expression of THP-1 cells
Geppert et al., Mol Med 1994 : In RAW 264.7 mouse macrophages, both ERK2 and MEK1 activity are induced by LPS treatment