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IL2 — TCF3

Text-mined interactions from Literome

Chow et al., Mol Cell Biol 1999 : Requirement for transcription factor NFAT in interleukin-2 expression
Goebel et al., Transplantation 2001 : In human T lymphocytes, 16H5 attenuated both the tyrosine phosphorylation of STAT5 by IL-2 and the IL-2 induced DNA binding of this transcription factor
McDermott et al., Trends Mol Med 2002 (Familial Mediterranean Fever...) : Disorders of interleukin-1 processing and of regulation of nuclear factor kappaB transcription factor , and possibly defective apoptosis, might be involved in the pathogenesis of all but one of these disorders
Antov et al., J Immunol 2003 : In conventional CD4 ( + ) T cells, IL-2 triggers signaling pathways that promote proliferation and survival by activating the STAT5 transcription factor and by increasing the expression of the antiapoptotic protein, Bcl-2
Zheng et al., J Immunol 2007 (Autoimmune Diseases) : Although others have reported that IL-2 can directly enhance forkhead box protein P3 (Foxp3) transcription factor expression by natural CD4 ( + ) CD25 ( + ) regulatory T cells, in this study, we report that the role of IL-2 on the generation of peripheral regulatory CD4 ( + ) cells is indirect
Sheikh et al., Hepatology 2008 (Hepatitis C...) : This transcription factor plays a key role in the expression of cytokines, tumor necrosis factor alpha (TNF-alpha), interleukin 6, interleukin 8, tumor growth factor beta, and Fas ligand
Chen et al., Immunity 2008 (Arthritis, Rheumatoid...) : IRF-4 binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor
Saraiva et al., Immunity 2009 : Interleukin-10 production by Th1 cells requires interleukin-12 induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose
Mitchell et al., J Immunol 2013 (Arenaviridae Infections) : Because IL-2 induces potent activation of the STAT5 transcription factor , we tested the role of STAT5 in CD8 ( + ) memory T cell differentiation and function using a model system in which STAT5 activity is inducibly abrogated upon CD8 ( + ) T cell activation
Shibuya et al., Int Immunol 1989 : Involvement of a common transcription factor in the regulated expression of IL-2 and IL-2 receptor genes
Leung et al., Nature 1988 : We have now found evidence that a similar transcription factor is involved in the induction of IL-2R alpha expression by tat-I
Gilmour et al., Proc Natl Acad Sci U S A 1995 : Interleukin 2 activates STAT5 transcription factor ( mammary gland factor ) and specific gene expression in T lymphocytes
Sung et al., J Biol Chem 1993 : Stimulation of interleukin-1 gene transcription may be caused by the stimulation of transcription factor activities, including those of AP-1, by these protein phosphatase inhibitors
Pahlavani et al., Mech Ageing Dev 1996 : The age related decline in IL-2 production has been shown to arise from a decline in IL-2 transcription, and a recent study suggests that the transcription factor NFAT ( nuclear factor of activated T cells ) may play a role in the decline in IL-2 transcription
Pahlavani et al., Free Radic Biol Med 1998 : Because IL-2 plays a crucial role in T cell proliferation and because the transcription factor NFAT ( nuclear factor of activated T cell ) plays a major role in the regulation of IL-2 transcription, the induction of NFAT as well as NF-KB and AP-1 DNA binding activities in nuclear extracts of the X/XO treated and untreated control cells was measured using a gel shift assay