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CXCR4 — STAM
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Malik et al., Mol Biol Cell 2010
:
Depletion of
STAM-1 by RNA interference and disruption of the arrestin-2/STAM-1 interaction accelerates agonist
promoted degradation of
CXCR4 , suggesting that STAM-1 via its interaction with arrestin-2 negatively regulates CXCR4 endosomal sorting
Malik et al., J Biol Chem 2012
:
Here, we report a novel
role for AIP4 and
STAM-1 in regulation of
CXCR4 signaling that is distinct from their function in CXCR4 trafficking