◀ Back to CXCR4

CXCR4 — IL12B

Text-mined interactions from Literome

Wan et al., Blood 2004 : The induction of interferon-gamma-inducible protein 10 ( IP-10 ) secretion by Hsp70L1 is not shared by Hsp70, and other functional differences include more potent stimulation of DC IL-12p70 , CC-chemokine, and CCR7 and CXCR4 expression by Hsp70L1. Immunization of mice with the hybrid peptide Hsp70L1-ovalbumin ( OVA ) ( 257-264 ) induces an OVA ( 257-264 ) -specific Th1 response and cytotoxic T lymphocyte ( CTL ) that results in significant inhibition of E.G7-OVA tumor growth
McClymont et al., J Immunol 2011 (Diabetes Mellitus, Type 1) : Naive Tregs were capable of upregulating expression of Th1 associated T-bet, CXCR3 , and IFN-? in response to IL-12
Poppensieker et al., Proc Natl Acad Sci U S A 2012 (Encephalomyelitis, Autoimmune, Experimental...) : CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells
Galli et al., Eur J Immunol 1998 : Similarly, in naive CD4+ T cells activated in the presence of IL-4 or IL-12 and infected with the same T-tropic strain, IL-4 up-regulated whereas IL-12 down-regulated both CXCR4 and HIV-1 expression ... The down-regulatory effect of IL-12 on CXCR4 expression was found to be dependent on its capacity to induce IFN-gamma production