Gene interactions and pathways from curated databases and text-mining

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BDNF — CXCR4

Text-mined interactions from Literome

Bachis et al., J Neurosci 2003 : Most importantly, BDNF reduced the levels of CXC chemokine receptor-4 (CXCR4) , a receptor that mediates HIV-1 gp120 induced apoptosis
Nosheny et al., Eur J Neurosci 2007 : Our data suggest that down-regulation of CXCR4 expression may contribute to the neuroprotective activity of BDNF against gp120 toxicity in the basal ganglia