Fukuyama et al., Biochem Biophys Res Commun 2005
(Hypertrophy) :
We examined the role of CREB in PGF ( 2alpha ) -induced hypertrophy of VSMCs. PGF ( 2alpha ) induced phosphorylation of CREB at serine 133, which is a critical marker of activation, after 5-10min of stimulation in a dose dependent manner
Chang et al., Int Endod J 2010
(Second Messenger Systems) :
PGF ( 2alpha ) induced both ERK and CREB/ATF-1 phosphorylation in pulp cells