Gene interactions and pathways from curated databases and text-mining

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CDH1 — ROCK2

Text-mined interactions from Literome

Chang et al., Cancer Res 2006 (Colonic Neoplasms...) : Inhibition of Rho kinases ( ROCK ), the RhoA effector proteins, also increased levels of E-cadherin and alpha-catenin and stimulated formation of adherens junctions
Ordóñez-Morán et al., J Cell Biol 2008 (Colonic Neoplasms) : As shown by the use of chemical inhibitors, dominant negative mutants and small interfering RNA, RhoA-ROCK , and p38MAPK-MSK1 activation is necessary for the induction of CDH1/E-cadherin , CYP24, and other genes and of an adhesive phenotype by 1,25 ( OH ) ( 2 ) D ( 3 ) ... As shown by the use of chemical inhibitors, dominant negative mutants and small interfering RNA, RhoA-ROCK , and p38MAPK-MSK1 activation is necessary for the induction of CDH1/E-cadherin , CYP24, and other genes and of an adhesive phenotype by 1,25 ( OH ) ( 2 ) D ( 3 )