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CASP10 — VIM
Text-mined interactions from Literome
Yang et al., Am J Pathol 2005
(Arthritis, Rheumatoid) :
Taken together, our findings suggest a unique
role for
caspase-4 in cleaving
vimentin and releasing cytosolic p53 for nuclear translocation, events that may regulate the sensitivity of RASFs to receptor mediated apoptosis
Catassi et al., Cell Mol Life Sci 2006
(Carcinoma, Non-Small-Cell Lung...) :
A cascade of events leading to apoptotic mitochondrial ` intrinsic ' pathway was observed in treated cells : ( 1 ) dephosphorylation of BAD serine136 ; ( 2 ) BAD dissociation from 14-3-3 followed by its association with BCL-XL ; ( 3 ) cytochrome c release ; ( 4 )
caspase-3 activation , and ( 5 ) cleavage of
vimentin
Lahat et al., PloS one 2010
(Neovascularization, Pathologic...) :
This proapoptotic response was abrogated after vimentin knockdown or by blockade of
caspase induced
vimentin degradation via caspase inhibitors or overexpression of mutated caspase-resistant vimentin