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IL2 — UGCG
Text-mined interactions from Literome
Wu et al., Eur J Immunol 1991
:
The suppression is observed at the protein and at the mRNA levels and it is not secondary to the
GCS induced inhibition of
IL2 production
Hasan et al., Age (Dordrecht, Netherlands) 2012
:
GCs also
inhibit interleukin-2 synthesis through suppressing T cell receptor signal that leads to loss of T cell activation, proliferation, and B-cell activation
Krouwels et al., Am J Respir Cell Mol Biol 1996
:
Interestingly, two categories of clones were distinguished based on the
effects of
GCS on
IL-2 production and IL-2R alpha expression and proliferation ; 1 ) In low IL-2 producers DEX blocked IL-2 production and decreased IL-2R alpha expression and proliferation ; 2 ) In high IL-2 producers DEX inhibited IL-2 production partially and enhanced IL-2R alpha expression and proliferation