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HAMP — IL6

Text-mined interactions from Literome

Dzikaite et al., J Hepatol 2006 (Disease Models, Animal...) : Regulatory effects of tumor necrosis factor-alpha and interleukin-6 on HAMP expression in iron loaded rat hepatocytes ... In the presence of serum, tumor necrosis factor-alpha, lipopolysaccharide and interleukin-6 increased HAMP expression in hepatocytes from both control and iron loaded rats
Nguyen et al., Am J Physiol Lung Cell Mol Physiol 2006 : IL-1 and IL-6 , which are important in HAMP augmentation in hepatocytes, also did not affect HAMP expression in alveolar macrophages
Jacolot et al., Blood Cells Mol Dis 2008 : Hepcidin transcription is clearly up-regulated by the pro-inflammatory cytokine IL-6 and down-regulated, in the case of iron depletion, at least via HIF transcription factors
Sow et al., J Leukoc Biol 2009 (Mycobacterium Infections) : Hepcidin is induced in hepatocytes during the acute-phase response by IL-6
Steinbicker et al., Blood 2011 (Anemia...) : Hepcidin is transcriptionally regulated by IL-6 and bone morphogenetic protein ( BMP ) signaling
Guan et al., J Nutr 2013 (Anemia, Iron-Deficiency) : In cells treated with 400 µg/mL of extract, phosphorylated mothers against decapentaplegic homolog proteins 1/5/8 levels were 80 % less than those of controls ( P < 0.001 ), and the inhibitory effect on interleukin-6 induced HAMP expression ( 65 % inhibition ) was weaker than the strong inhibition on bone morphogenetic protein 6-induced HAMP expression ( 97 % inhibition )