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BCL2L12 — CASP5
Text-mined interactions from Literome
Stegh et al., Genes Dev 2007
(Brain Neoplasms...) :
Mechanistically,
Bcl2L12 expression does not
affect cytochrome c release or apoptosome-driven
caspase-9 activation, but instead inhibits post-mitochondrial apoptosis signaling at the level of effector caspase activation
He et al., Cell Signal 2008
:
Involvement of G proteins of the Rho family in the regulation of
Bcl-2-like protein expression and
caspase 3
activation by Gastrins ... Since in other systems G proteins of the Rho family inhibit apoptosis via interaction with proteins of the Bcl-2 family, leading to changes in caspase activities, we have compared the role of Rho family G proteins in regulation of
Bcl-2-like ( Bad/Bax/Bcl-xl ) protein expression and
caspase 3
activation by Ggly and Gamide
Stegh et al., Proc Natl Acad Sci U S A 2008
(Glioblastoma) :
Bcl2L12 mediated inhibition of effector
caspase-3 and caspase-7 via distinct mechanisms in glioblastoma ... Whereas Bcl2L12 mediated neutralization of caspase-7 maturation involves physical interaction, the mechanism governing
Bcl2L12 mediated inhibition of
caspase-3 activity is not known