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EGF — IQGAP1
Text-mined interactions from Literome
Heil et al., J Biol Chem 2011
(MAP Kinase Signaling System) :
Specifically, the
EGF induced tyrosine phosphorylation of
IQGAP1 that is thought to function in assembling signaling intermediates at IQGAP1 scaffolds in the subplasmalemmal region is markedly reduced in cells overexpressing S100P but not in cells expressing an S100P mutant deficient in IQGAP1 binding
Casteel et al., J Biol Chem 2012
(Breast Neoplasms) :
EGF- or RhoC induced migration
required IQGAP1 , but IQGAP1 stimulated migration independently of RhoC, placing IQGAP1 downstream of RhoC