Laudes et al., J Biol Chem 2004
:
In addition, FBI-1 reduced the transcriptional activity of the cyclin A promoter
Laudes et al., J Mol Med (Berl) 2008
:
Interestingly, FBI-1 repressed cyclin A promoter activity through an indirect mechanisms that did not involve direct binding of FBI-1 to the promoter sequence, but rather FBI-1 inhibition of transcriptional activator Sp1 binding to a regulatory element at -452 to -443