Gene interactions and pathways from curated databases and text-mining

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FUT1 — TNF

Text-mined interactions from Literome

Saile et al., Eur J Cell Biol 2001 : The aim of this study was to investigate the possible mechanisms responsible for the spontaneous apoptosis and for the anti-apoptotic effect of TGF-beta and TNF-alpha on activated HSC
Li et al., Yao Xue Xue Bao 2001 : Adhesion molecular VCAM-1 and ICAM-1 protein and mRNA ( rather than ICAM-1 ) expression in HSC induced by TNF-alpha ( 50 U.mL-1 ) were inhibited significantly by hydrocortisone at 1 x 10 ( -6 ) -10 ( -5 ) mol.L-1
Hou et al., Yao Xue Xue Bao 2001 : To study the effects of isorhapotigenin ( Iso ) on interleukin-8 (IL-8) production and mRNA expression in normal human synovial cells (HSC) induced with TNF alpha ... The further study indicated that Iso at the concentrations of 1 x 10 ( -6 ) mol.L-1 to 1 x 10 ( -5 ) mol.L-1 inhibited IL-8 mRNA expression in HSC induced with TNF alpha ( 0.25 U.mL-1 )
Sugino et al., J Gastroenterol Hepatol 2008 (Body Weight...) : MCD mice developed steatohepatitis accompanied by mild fibrosis with an increase in lipid peroxidation, hepatic stellate cell (HSC) activation , and the augmented mRNA expression of tumor necrosis factor-alpha , transforming growth factor-beta1 and procollagen alpha1 ( I )
Su et al., Cytokine 2010 (Endotoxemia) : The effect of HSC70 on TNF-alpha was less robust than endotoxin preconditioning ( 79.7 % and 75.0 % reduction in TNF-alpha levels in plasma and heart tissue, respectively ) ; however, HSC70 and endotoxin preconditioning had comparable effects on ICAM-1 levels in heart tissue
Fujiwara et al., J Am Coll Surg 2013 (Pancreatic Neoplasms) : In vitro, we assessed that FUT175 inhibited both TNF-a- and gemcitabine induced NF-?B activation and enhanced apoptosis in human pancreatic cancer cell lines ( MIAPaCa-2 and AsPC-1 ) ... In vitro, FUT175 inhibited both TNF-a- and gemcitabine induced NF-?B activation and enhanced induction of apoptosis
Osawa et al., PloS one 2013 : However, the roles of TNF-a on hepatic stellate cell (HSC) activation and liver fibrosis are complicated and remain controversial
Liu et al., J Pathol 2013 (Disease Models, Animal...) : JTE-013 or S1PR2-siRNA attenuated the effect of HPPCn on HSC activation induced by tumour necrosis factor-a (TNF-a)
Schuettpelz et al., Frontiers in immunology 2013 : Type I and II interferons, tumor necrosis factor , and lipopolysaccharide (LPS) directly stimulate HSC proliferation and differentiation, thereby increasing the short-term output of mature effector leukocytes