Gene interactions and pathways from curated databases and text-mining

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NFKB1 — PIGR

Text-mined interactions from Literome

Ackermann et al., Immunology 2004 : In studies using human intestinal epithelial cells ( HT29 ), multiple inhibitors of the transcription factor nuclear factor-kappaB (NF-kappaB) , including a dominant negative IkappaBalpha-serine mutant, inhibited both IL-4- and IFN dependent increases in pIgR expression
Hinojosa et al., J Infect Dis 2009 (Inflammation...) : During pneumonia, aged mice had reduced levels of pIgR and PAFr and less NFkB activation , despite greater bacterial burden
Bruno et al., Immunol Invest 2010 : Induction of pIgR expression in HT-29 cells required NF-kappaB signaling but not MAPK signaling, in contrast to the requirement for both NF-kappaB and MAPK signaling for induction of pro-inflammatory genes