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CASP12 — UBE2K

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: CASP12 — UBE2K (direct interaction, enzymatic study) Song et al., J Cell Biol 2008*

Text-mined interactions from Literome

Suzuki et al., Proc Natl Acad Sci U S A 2001 : These results demonstrate that the ubiquitin-protein ligase activity of XIAP promotes the degradation of caspase-3 , which enhances its anti-apoptotic effect
Song et al., J Cell Biol 2008 : E2-25K/Hip-2 regulates caspase-12 in ER stress mediated Abeta neurotoxicity ... This increase in E2-25K/Hip-2 also induces proteolytic activation of caspase-12 through its ability to induce calpainlike activity ... E2-25K/Hip-2 is thus an essential upstream regulator of the expression and activation of caspase-12 in ER stress mediated Abeta neurotoxicity