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PI3 — TCF12
Text-mined interactions from Literome
Lee et al., Mol Cancer Res 2004
(Breast Neoplasms...) :
Stromal cell derived factor 1alpha ( SDF-1alpha ; CXCL12 ) stimulation of breast cancer cells resulted in
phosphoinositide 3-kinase (PI-3K) activation, AKT phosphorylation, and
activation of the FKHRL1
transcription factor
Huang et al., Chem Biol Interact 2009
(Glioma...) :
Further ( Ac ) ( 5 ) GP also exerted an inhibitory effect on
phosphoinositide 3-kinase (PI3K) protein expression, phosphorylation of extracellular signal regulated kinases 1 and 2 ( ERK1/2 ) and
inhibition of activation of
transcription factor nuclear factor kappa B (NF-kappaB), c-Fos, c-Jun
Yen et al., J Biol Chem 2011
(MAP Kinase Signaling System) :
PKA,
PI3K , and ERK inhibitors abolished PGE2- and cAMP induced c-Fos and MMP-9 up-regulation, and ERK activation was
required for the binding of activator protein 1 (AP-1)
transcription factor to the MMP-9 promoter