◀ Back to FOXP3
FOXP3 — IL5
Text-mined interactions from Literome
Leech et al., J Immunol 2007
(Asthma...) :
Most convincingly, transfer of CD4 ( + ) CD25 ( + )
Foxp3 ( + ) T cells from Ag naive mice ( natural Tregs ) abolished AAI, decreased dMLN IL-5 and IL-13 secretion, increased dMLN IL-10 secretion, abolished IgE, and decreased IgG1 Abs. Blocking IL-10 receptor function in vivo did not block the anti-inflammatory function of transferred natural Tregs but did
restore dMLN
IL-5 and IL-13 secretion
Chaput et al., Gut 2009
(Adenocarcinoma...) :
Finally,
interleukin 6 and TGF beta 1 synergistically
induced the generation of CD8 ( + ) CD25 ( + )
Foxp3 ( + ) T cells ex vivo