Gene interactions and pathways from curated databases and text-mining
CASP3: top 25 interacting genes (chr4:185548849-185570629)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only CASP3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with CASP3, not among the Top 25
Other genes interacting with CASP3. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AKT3 ▸ XIAP ▸ IL1B ▸ FASLG ▸ MAPK3 ▸ BCL6 ▸ BCL3 ▸
BCL9 ▸ DIABLO ▸ BCL5 ▸ IL1A ▸ EPHB2 ▸ IRF6 ▸ MAPK1 ▸
MAPK7 ▸ MAPK15 ▸ MAPK8 ▸ MAPK14 ▸ MAPK9 ▸ MAPK10 ▸ MAPK13 ▸
MAPK6 ▸ MAPK4 ▸ MAPK12 ▸ MAPK11 ▸ IFNG ▸ CASP9 ▸ CASP8 ▸
APAF1 ▸ CASP12 ▸ CASP1 ▸ CASP2 ▸ CAPN1 ▸ DNTT ▸ CAPN10 ▸
CAPN13 ▸ CAPN6 ▸ CAPN3 ▸ CAPN9 ▸ CAPN7 ▸ CAPN2 ▸ CAPN12 ▸
CASP6 ▸ CAPN15 ▸ CAPN8 ▸ CAPN11 ▸ CAPN14 ▸ CAPN5 ▸ IL18 ▸
FADD ▸ CASP10 ▸ CASP14 ▸ CASP5 ▸ CASP4 ▸ CASP7 ▸ CASP16 ▸
ASIP ▸ STS ▸ MCL1 ▸ MMP2 ▸ MMP9 ▸ MMP11 ▸ JUN ▸
MMP12 ▸ MMP14 ▸ MMP3 ▸ NLRP3 ▸ MMP21 ▸ MMP17 ▸ MMP7 ▸
MMP15 ▸ MMP16 ▸ MMP24 ▸ MMP10 ▸ MMP13 ▸ MMP27 ▸ MMP20 ▸
MMP8 ▸ CDKN1A ▸ MMP19 ▸ MMP1 ▸ MMP28 ▸ MMP25 ▸ MMP26 ▸
PDCD11 ▸ PDCD5 ▸ PDCD10 ▸ RNF19A ▸ PDCD4 ▸ PDCD6 ▸ PDCD1 ▸
PDCD7 ▸ PDCD2 ▸ CYCS ▸ CFLAR ▸ NA ▸ IGF1 ▸ ANXA5 ▸
PCBD1 ▸ TGFB1 ▸ AHSA1 ▸ HLA-DRB1 ▸ MPZ ▸ PIK3R1 ▸ INS ▸
PIK3CA ▸ EPO ▸ PRKCD ▸ NLRC4 ▸ MYLIP ▸ VEGFA ▸ PI3 ▸
DDIT3 ▸ IL6 ▸ TAT ▸ PCNA ▸ GRAP2 ▸ NOS2 ▸ DFFA ▸
PRDX2 ▸ TNFRSF1A ▸ GSK3B ▸ BIRC2 ▸ DISC1 ▸ CRK ▸ EGF ▸
PAK2 ▸ DISC2 ▸ CTSB ▸ NGF ▸ IL8 ▸ SOD1 ▸ CAST ▸
CTNNB1 ▸ PTGS2 ▸ EIF2AK2 ▸ IL4 ▸ DFFB ▸ LEP ▸ NOS1 ▸
BID ▸ ABL1 ▸ DNASE2 ▸ ALPI ▸ DNASE1 ▸ MYC ▸ SOD2 ▸
HGF ▸ FOS ▸ IRF1 ▸ P2RX7 ▸ ROCK1 ▸ APP ▸ TCF4 ▸
MAP3K1 ▸ CAT ▸ BDNF ▸ CDK2 ▸ CTSD ▸ IFNB1 ▸ IFI27 ▸
APEH ▸ BCR ▸ IL16 ▸ HTRA2 ▸ TCF24 ▸ TCF15 ▸ CSF2 ▸
TCF3 ▸ TCF19 ▸ GZMB ▸ IL10 ▸ BIRC3 ▸ TCF21 ▸ RAC1 ▸
BMP1 ▸ NOD2 ▸ HSPA5 ▸ TCF7 ▸ NOS3 ▸ SOD3 ▸ APOB ▸
FGF2 ▸ TCF12 ▸ HDAC2 ▸ TCF23 ▸ PRKDC ▸ UPK3B ▸ TLR2 ▸
BIRC7 ▸ TCF20 ▸ NOX1 ▸ NFKBIA ▸ BMP4 ▸ TCF25 ▸ RIPK1 ▸
GAL ▸ TLR4 ▸ HMGB1 ▸ ITIH4 ▸ PPARA ▸ HDAC1 ▸ IL2 ▸
AIM2 ▸ CA2 ▸ CDC73 ▸ NLRP1 ▸ MAP2K1 ▸ CSF3 ▸ STAT1 ▸
MAGT1 ▸ ATP5O ▸ TLR3 ▸ POLDIP2 ▸ CD8A ▸ PML ▸ NOX4 ▸
ADCYAP1 ▸ BAD ▸ LMNB1 ▸ ARSK ▸ RIPK2 ▸ TLR5 ▸ BMP2 ▸
BMP6 ▸ BMP3 ▸ RB1 ▸ RAD51 ▸ HSPB1 ▸ NOD1 ▸ KRT18 ▸
BMP7 ▸ STAT3 ▸ NOX3 ▸ SMPD2 ▸ CDK5 ▸ PAF1 ▸ PDLIM7 ▸
BMP15 ▸ CD79A ▸ PPP2R1A ▸ BMP5 ▸ ENDOG ▸ WDR61 ▸ LEO1 ▸
PRNP ▸ IL3 ▸ APC ▸ HPR ▸ PPP2R2B ▸ SNAP25 ▸ MST1 ▸
BMP10 ▸ CARD8 ▸ IL33 ▸ IL5 ▸ IL11 ▸ AGTR1 ▸ PPP2CA ▸
TLR7 ▸ IL7 ▸ NOX5 ▸ CTR9 ▸ ARID1A ▸ PTX3 ▸ WAS ▸
IL21 ▸ HIF1A ▸ ABCC6 ▸ CREB3 ▸ IGF2 ▸ IL15 ▸ GP9 ▸
LPA ▸ ICAM1 ▸ PLCG1 ▸ SMARCC1 ▸ CDH1 ▸ ANGPT2 ▸ LMNB2 ▸
IL25 ▸ SMARCA4 ▸ TRAF6 ▸ GP5 ▸ CDC6 ▸ CSE ▸ RBBP7 ▸
FOXO3 ▸ BOC ▸ RIPK3 ▸ ANXA1 ▸ RBBP4 ▸ SMARCD1 ▸ GSN ▸
CD4 ▸ SMARCA2 ▸ TLR1 ▸ ACTL6A ▸ CREB1 ▸ SMARCB1 ▸ PGP ▸
PTX4 ▸ IL20 ▸ GP6 ▸ SYK ▸ GP2 ▸ TNFRSF1B ▸ EIF2S1 ▸
TLR10 ▸ CCDC88A ▸ SMARCC2 ▸ BIRC6 ▸ CXCL9 ▸ MAP2K2 ▸ SMARCE1 ▸
SMARCD2 ▸ HTT ▸ IL24 ▸ CREB5 ▸ TXN ▸ JAK2 ▸ MET ▸
EGFR ▸ ANGPT1 ▸ TLR8 ▸ NPS ▸ IL37 ▸ TLR6 ▸ MUC12 ▸
CDA ▸ ACHE ▸ MUC6 ▸ PTEN ▸ IL32 ▸ IKBKB ▸ ROCK2 ▸
MDM2 ▸ MUC13 ▸ IL9 ▸ HSPD1 ▸ MEFV ▸ BECN1 ▸ HMOX1 ▸
MUC17 ▸ TOP1 ▸ RAF1 ▸ IRF3 ▸ IL19 ▸ IL27 ▸ IL34 ▸
TRAF1 ▸ MUC2 ▸ BRCA1 ▸ MSC ▸ PRKCA ▸ MUC20 ▸ MUC7 ▸
MUC15 ▸ RENBP ▸ CDK8 ▸ UCN ▸ SP1 ▸ IL13 ▸ RRAS ▸
CARD11 ▸ MUC16 ▸ MUC21 ▸ CCND1 ▸ CD79B ▸ CARD6 ▸ MUC8 ▸
SMPD1 ▸ MUC4 ▸ CARD9 ▸ PLD1 ▸ GATA1 ▸ MUC19 ▸ PAK1 ▸
IL31 ▸ MUC1 ▸ LYN ▸ SYT1 ▸ IL26 ▸ KDR ▸ TLR9 ▸
IL22 ▸ STX1A ▸ MUC22 ▸ PPARG ▸ LYPLA1 ▸ PTHLH ▸ PRKACG ▸
CEP128 ▸ CARD17 ▸ NPM1 ▸ VIM ▸ BCL2L12 ▸ CEP72 ▸ CEP19 ▸
GRB7 ▸ ZGLP1 ▸ CD47 ▸ PRKAR2A ▸ MIF ▸ SOAT1 ▸ GDNF ▸
SEC14L2 ▸ ATF2 ▸ MAP2K6 ▸ CCR7 ▸ PRKCG ▸ CEP135 ▸ PLOD2 ▸
BIRC8 ▸ PTBP1 ▸ DST ▸ HIP1 ▸ IGF1R ▸ CEP68 ▸ CEP170 ▸
PRKAR1A ▸ VCP ▸ CEP104 ▸ GRB10 ▸ ALB ▸ RAD17 ▸ VDAC1 ▸
CEP78 ▸ DERL1 ▸ PRKAB2 ▸ TRAF2 ▸ EHMT1 ▸ CDK4 ▸ SETD2 ▸
ME2 ▸ ARSA ▸ GRB14 ▸ SLC9A1 ▸ PRKACB ▸ SLC17A5 ▸ PRKAA1 ▸
CEP164 ▸ CEP97 ▸ CALM3 ▸ PRKAG2 ▸ TCHP ▸ E2F1 ▸ HSP90AA1 ▸
IRF5 ▸ FOXO1 ▸ CEP250 ▸ CARD18 ▸ WNK1 ▸ ATG5 ▸ PRKAA2 ▸
DES ▸ PIDD ▸ PTK2 ▸ CTNND1 ▸ IRF4 ▸ CEP41 ▸ MAP2K4 ▸
SLCO6A1 ▸ PSMD10 ▸ CEP76 ▸ PRKAB1 ▸ BIRC5 ▸ PSEN1 ▸ CEP290 ▸
TRAF3 ▸ NTF3 ▸ IKBKG ▸ FUT1 ▸ WNT1 ▸ CEP95 ▸ H2AFX ▸
CEP44 ▸ PANX1 ▸ MAP2K3 ▸ PNPLA2 ▸ PRKAR1B ▸ HIST2H2BE ▸ SUB1 ▸
HSF1 ▸ SETBP1 ▸ GUCY2D ▸ SKP1 ▸ ALK ▸ CEP120 ▸ CEP89 ▸
NPY6R ▸ CEP350 ▸ ELAVL1 ▸ CEP57 ▸ CARD14 ▸ VIMP ▸ CEP63 ▸
PPP1R3A ▸ CEP192 ▸ CEP85 ▸ PRKAR2B ▸ PEA15 ▸ ATF5 ▸ TNFRSF10A ▸
CARD16 ▸ MPST ▸ IRF2 ▸ BACE1 ▸ ARC ▸ LAT ▸ CCNH ▸
CEP112 ▸ MAP2K5 ▸ CARD10 ▸ CEP55 ▸ MAP2K7 ▸ GRB2 ▸ TARDBP ▸
TIMP3 ▸ EPX ▸ PRKAG1 ▸ RASA1 ▸ CEP152 ▸ ADIPOQ ▸ HUNK ▸
CUL1 ▸ CCL2 ▸ CEP70 ▸ CTSL ▸ PLD2 ▸ CD40 ▸ CFL1 ▸
MED14 ▸ CDK14 ▸ GNA11 ▸ CISH ▸ JAK1 ▸ HRK ▸ RAD21 ▸
CD8B ▸ APOE ▸ SMAD7 ▸ CALR ▸ GRP ▸ CRYAB ▸ ANGPT4 ▸
NLRP7 ▸ SHH ▸ CCR2 ▸ CSF1 ▸ CDCA5 ▸ STC1 ▸ CA8 ▸
CTNNBL1 ▸ HTRA3 ▸ GLI1 ▸ NOTCH1 ▸ THBS1 ▸ GHSR ▸ CCR1 ▸
DAP3 ▸ GNRH1 ▸ SAA1 ▸ MAP2 ▸ SMAD4 ▸ MST1R ▸ STSP1 ▸
VDAC3 ▸ IGFBP3 ▸ ING1 ▸ IL1RN ▸ NUP43 ▸ SATB1 ▸ PRG3 ▸
KLK3 ▸ E2F2 ▸ CPOX ▸ BCAP31 ▸ IFI44 ▸ MTX1 ▸ PTH ▸
ANXA6 ▸ PLD3 ▸ MT4 ▸ PTPN11 ▸ NUP214 ▸ STX2 ▸ EDNRA ▸
IFNA2 ▸ MED12 ▸ SDS ▸ CDK3 ▸ S100A12 ▸ ETS2 ▸ CYR61 ▸
TRAF5 ▸ PTCH1 ▸ EIF4G3 ▸ MED15 ▸ ATG3 ▸ MT3 ▸ NLRC5 ▸
TFAP2A ▸ PAEP ▸ MAP3K7 ▸ MED21 ▸ MED7 ▸ NAB1 ▸ IAPP ▸
TNFRSF10B ▸ RAD52 ▸ CCNC ▸ CHUK ▸ MTOR ▸ DAXX ▸ SERPINB9 ▸
DIDO1 ▸ CDK15 ▸ ADH5 ▸ GPI ▸ TYR ▸ PC ▸ CCR5 ▸
RBL2 ▸ TRAF4 ▸ PAN3 ▸ FLT3 ▸ PSENEN ▸ TGFB3 ▸ CDK16 ▸
NLRP5 ▸ CCR8 ▸ SERPINA1 ▸ BNIP3 ▸ CDK6 ▸ TNFSF12 ▸ CDK19 ▸
NANOG ▸ CCL19 ▸ EIF4G2 ▸ KMT2A ▸ NTN1 ▸ DHCR24 ▸ LRP1 ▸
TRAF7 ▸ IFIH1 ▸ CDK20 ▸ ETS1 ▸ CDK17 ▸ SERPINF1 ▸ KLF4 ▸
XAF1 ▸ HRD ▸ IRF9 ▸ CIB1 ▸ CDK13 ▸ PPT1 ▸ EMP3 ▸
VDAC2 ▸ RARA ▸ SMAD3 ▸ CALB1 ▸ NODAL ▸ NUP153 ▸ C22orf29 ▸
SLPI ▸ LGALS1 ▸ EEF1A2 ▸ RUNX3 ▸ CDK18 ▸ CDC42 ▸ MTA1 ▸
HMGCR ▸ EMP2 ▸ PAWR ▸ TET3 ▸ MICE ▸ APIP ▸ NAIP ▸
EML2 ▸ GPX3 ▸ PRG2 ▸ ABCD1 ▸ CDK7 ▸ MED23 ▸ TAC3 ▸
CCK ▸ CDK1 ▸ TRA ▸ CFTR ▸ ACIN1 ▸ PLK1 ▸ RAC2 ▸
HDAC4 ▸ WNT3A ▸ GSTT1 ▸ RAD18 ▸ GYS1 ▸ IFNA5 ▸ CCR3 ▸
CDK9 ▸ SERP2 ▸ HDAC6 ▸ CTRL ▸ CXCL13 ▸ SREBF2 ▸ HTRA1 ▸
TGM2 ▸ NR0B1 ▸ CCR6 ▸ ID3 ▸ RAD50 ▸ TAC4 ▸ DLG1 ▸
MED24 ▸ NUP210 ▸ FHIT ▸ NTF4 ▸ TET2 ▸ AFP ▸ IRF8 ▸
DNAJC5 ▸ UCP2 ▸ CPA1 ▸ PLD5 ▸ PARG ▸ GJA1 ▸ PLD4 ▸
NANOS2 ▸ PSMB9 ▸ ATM ▸ EIF4G1 ▸ MED8 ▸ CAPNS1 ▸ CCR9 ▸
XRCC6 ▸ MED17 ▸ SIVA1 ▸ IRS1 ▸ CCR10 ▸ ADM ▸ HCLS1 ▸
TNFRSF8 ▸ ODC1 ▸ GPX1 ▸ TET1 ▸ CALML3 ▸ EMP1 ▸ NPPA ▸
DAPK2 ▸ KLKB1 ▸ COP ▸ MED6 ▸ RHO ▸ NACA ▸ JAK3 ▸
QRICH2 ▸ AIP ▸ CDK10 ▸ RIPK4 ▸ HIPK2 ▸ SPP1 ▸ NAB2 ▸
APOBEC3D ▸ MED4 ▸ MED1 ▸ LRRC59 ▸ PAN2 ▸ IRF7 ▸ SHC1 ▸
MTA2 ▸ NUP62 ▸ PGF ▸ DYRK1A ▸ TMED7 ▸ ACR ▸ ITCH ▸
RAD1 ▸ MED26 ▸ CDK12 ▸ CD2 ▸ ERVK-6 ▸ PMEL ▸ RAC3 ▸
ANG ▸ IDO1 ▸ BAG3 ▸ SEPT4 ▸ NUAK1 ▸ APEX1 ▸ PXN ▸
MED13 ▸ QRICH1 ▸ SREBF1 ▸ BLM ▸ MTA3 ▸ VIP ▸ PLD6 ▸
ANP32A ▸ ACSM3 ▸ FAM168B ▸ PIN1 ▸ MED25 ▸ GYS2 ▸ FAF1 ▸
HTRA4 ▸ MME ▸ PRG4 ▸ CCR4 ▸ TSC22D3 ▸ CENPK ▸ FKBP4 ▸
E2F3 ▸ TAC1 ▸ PDGFB ▸ ACAD8 ▸ ELANE ▸ PIP5K1A ▸ NGFRAP1 ▸
BIRC4 ▸ MAP4K1 ▸ SAV1 ▸ MAPK8IP3 ▸ PTMA ▸ NUMA1 ▸ NUCB2 ▸
TP73 ▸ UBE4B ▸ BCAR1 ▸ PDE10A ▸ IQGAP1 ▸ AIFM1 ▸ THAP11 ▸
PDE5A ▸ CD247 ▸ MAP3K14 ▸ AKAP8 ▸ CDC2L2 ▸ KARS ▸ NFE2L2 ▸
SARS2 ▸ STK24 ▸ RNF2 ▸ LPAR1 ▸ NR3C1 ▸ GMNN ▸ MLH1 ▸
NVL ▸ IFT57 ▸ PICALM ▸ TRIM28 ▸ ZBTB16 ▸ RABEP1 ▸ GAS2 ▸
HNRNPD ▸ SDC2 ▸ DSG1 ▸ MAPT ▸ DSG3 ▸ HEY2 ▸ NDUFS1 ▸
MEF2A ▸ FUS ▸ AR ▸ EIF3S10 ▸ YWHAG ▸ NEO1 ▸ YWHAE ▸
HNRNPU ▸ EIF4B ▸ MDC1 ▸ UBC ▸ ACTA1 ▸ BMX ▸ IL1R2 ▸
SYF2 ▸ LPAR3 ▸ EIF3J ▸ PPARGC1A ▸ COPS6 ▸ ARHGDIA ▸ PLA2G4A ▸
HNRNPA0 ▸ CDC2L1 ▸ NFATC2 ▸ ARHGDIB ▸ ATG4D ▸ CTTN ▸ CAD ▸
PRF1 ▸ SOCS5 ▸ ATN1 ▸ PLA2G4B ▸ PSIP1 ▸ EIF4A1 ▸ RBX1 ▸
PLEKHO1 ▸ GRIPAP1 ▸ DCTN1 ▸ FBXW11 ▸ KEAP1 ▸ TNS4 ▸ NGFR ▸
CDK11A ▸ DSG2 ▸ NMT2 ▸ ACVR1C ▸ HRAS ▸ PPP3CA ▸ IL1R1 ▸
TNFRSF25 ▸ GZMM ▸ GORASP1 ▸ CDK11B ▸ UNC5B ▸ WNK3 ▸ SCAF11 ▸
PTGES3 ▸ DBNL ▸ FUK ▸
Data information
Please see the Gene Interactions Track Manual.