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BGLAP — RUNX2
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Koga et al., Nat Med 2005
:
Overexpression of NFATc1 stimulates Osterix dependent activation of the Col1a1 ( encoding type I collagen ) promoter, but not
Runx2 dependent activation of the
Bglap1 ( encoding osteocalcin ) promoter
Komori et al., Cell Tissue Res 2010
:
However, overexpression of
Runx2 inhibits osteoblast maturation and
reduces Col1a1 and
Bglap expression ... The inhibition of
RUNX2 in mature osteoblasts does not
reduce the expression of Col1a1 and
Bglap in mice