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Kurada et al., J Biol Chem 2009
(Neoplasms) :
Endogenous MADD knockdown, however, did not affect epidermal growth factor induced MAPK activation thereby demonstrating the specific requirement of MADD for TNF receptor mediated MAPK activation
Schievella et al., J Biol Chem 1997
:
Importantly, we have found that overexpression of MADD activates the mitogen activated protein ( MAP ) kinase extracellular signal regulated kinase ( ERK ), and expression of the MADD death domain stimulates both the ERK and c-JUN N-terminal kinase MAP kinases and induces the phosphorylation of cytosolic phospholipase A2