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IRF6 — P2RX7

Text-mined interactions from Literome

Zhang et al., Sheng Li Xue Bao 2005 : P2X7 receptor expression in PBMC was up-regulated by interleukin-2, -4, -6 ( IL-2, IL-4, IL-6 ) tumour necrosis factor-alpha (TNF-alpha), lipopolysaccharide (LPS) and heat inactivated Staphylococcus aureus Cowan strain I ( SAC ) ... Furthermore, LPS and M-CSF could up-regulate P2X7 receptor expression in monocytes, while IFN-gamma, TNF-alpha and GM-CSF had weak effects, but pretreatment with these inducers could not further enhance LPS stimulated P2X7 receptor expression in monocytes
Raouf et al., Neuropharmacology 2007 : Differential regulation of microglial P2X4 and P2X7 ATP receptors following LPS induced activation
Csölle et al., J Neuroimmunol 2010 : Peripheral origin of IL-1beta production in the rodent hippocampus under in vivo systemic bacterial lipopolysaccharide (LPS) challenge and its regulation by P2X(7) receptors
Kim et al., Neurol Res 2013 (Inflammation) : These findings indicate that P2X7R may be involved in LPS induced inflammatory response in neurons, and that p65-Ser311 NF-kappaB phosphorylation may compensate for the loss function of P2X7R by as yet unknown factors
Li et al., Mol Med 2013 : As did P2X7R antagonists ( for example, oxidized ATP, oATP ), CBX also effectively attenuated LPS induced P2X7R/panx-1 channel activation ( as judged by Lucifer Yellow dye uptake ) and PKR phosphorylation in primary peritoneal macrophages