Gene interactions and pathways from curated databases and text-mining

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IL6 — LRG1

Text-mined interactions from Literome

Shirai et al., Biochem Biophys Res Commun 2009 (Acute-Phase Reaction...) : In this study, we found that LRG was induced by recombinant human IL-6 in human hepatoma HepG2 cells ... The induction of LRG by IL-6 was up-regulated synergistically with either IL-1beta or TNFalpha in a pattern similar to those for type 1 acute-phase proteins
Serada et al., Inflamm Bowel Dis 2012 (Colitis, Ulcerative...) : Tumor necrosis factor alpha ( TNF-a ), IL-6 , and IL-22, serum levels of which were elevated in patients with active UC, could induce LRG expression in COLO205 cells