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IL6 — IRF3

Text-mined interactions from Literome

Kim et al., Immunology 2008 : Therefore, dsRNA induced IL-6 production is dependent on mitogen activated protein kinases and type I IFN production is dependent on IRF3 in brain astrocytes
Mudter et al., Inflamm Bowel Dis 2011 (Colitis...) : In contrast to DSS colitis, IRF4 deficiency was protective in T-cell dependent transfer colitis associated with reduced RORa/?t levels and impaired IL-6 , IL-17a, and IL-22 production, suggesting that IRF4 acts as a master regulator of mucosal Th17 cell differentiation
Moore et al., Virology 2011 : In contrast SJL-IRF3 increased IL-6 , ISG56 and IFNß in response to TMEV
Ysebrant de Lendonck et al., Proc Natl Acad Sci U S A 2013 : Interferon regulatory factor 3 controls interleukin-17 expression in CD8 T lymphocytes
Harroch et al., J Biol Chem 1993 : The dissociation between induction of mRNAs and of protein binding observed suggests that the activity of the IRF proteins is regulated by IL-6