Gene interactions and pathways from curated databases and text-mining

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ATP8A2 — IL6

Text-mined interactions from Literome

Tsivkovskii et al., FEMS Immunol Med Microbiol 2011 (Chronic Disease...) : In vitro studies in human lung epithelial cell lines showed that levofloxacin led to a dose related reduction in IL-6 and IL-8 concentrations, with 300 µg mL(-1) resulting in the reduction of levels of IL-6 by fourfold and IL-8 by twofold ( P < 0.05 ) ; in contrast, tobramycin increased IL-6 levels by 50 %, but had no effect on IL-8
Wallberg et al., Eur J Appl Physiol 2011 : In the 24-h protocol IL-6 level was elevated from 0.76 ± 0.48 pg mL(-1) at rest to 7.16 ± 2.70 pg mL(-1) at 6 h, and increased further to 10.58 ± 1.04 pg mL(-1) at 12 h, but remained thereafter unchanged at 24 h, ( 10.89 ± 0.36 pg mL(-1) )
Hostanska et al., Nat Immun 1995 : Regarding cytokine secretion, IL-6 and TNF-alpha production was induced by 10 ng/ml ML-I
Bresser et al., Eur Respir J 1997 (Bronchitis...) : A suspension of 10 ( 7 ) and 10 ( 8 ) colony forming units ( cfu ) x mL(-1) of H. influenzae, persisting and nonpersisting, induced a dose- and time dependent production of IL-6 and IL-8 by the human pulmonary mucoepidermoid carcinoma derived cell line H292, but levels of IL-6 were lower after exposure to persisting H. influenzae ( p < 0.05 )