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FGF2 — FOS
Text-mined interactions from Literome
Mohan et al., J Biol Chem 2000
(Neovascularization, Pathologic) :
Using cultured corneal cells, we show that
FGF-2 stimulates DNA binding activity of transcription factor AP-1 but not NF-kappaB and that
AP-1 stimulation is
inhibited by curcuminoids
Varghese et al., Endocrinology 2000
:
bFGF stimulated the binding of nuclear factors to the collagenase
AP-1 site by 3- to 4-fold, as determined by electrophoretic mobility shift assays
Schwarz et al., J Immunol 2001
(Inflammation) :
This was associated with constitutive induction of the proinflammatory NF-kappaB dependent cytokines IL-1beta, IL-6, and TNF-alpha, and chemokines monocyte chemoattractant protein-1 and IL-8, as well as the
AP-1 dependent
basic fibroblast growth factor
Yasui et al., Digestion 2004
:
FGF-2 induced
AP-1-DNA binding activity, and the c-Jun/AP-1 inhibitor curcumin attenuated the FGF-2 induced MMP-1, -3 and TIMP-1 mRNA expression
Cuevas et al., Oncogene 2005
:
Both
FGF-2 and phorbol ester-inducible urokinase-type plasminogen activator ( uPA ) expression
requires AP-1 binding to an enhancer element in the uPA promoter, and we have previously shown that FGF-2 or PMA induction of uPA expression is strongly dependent on MEKK1
Wu et al., Mol Cell Biol 2007
:
Fibroblast growth factor 2 (FGF-2) and cortisol
induced AP-1 and GR occupancy, respectively, at a Notch4 promoter composite response element consisting of an imperfect half-glucocorticoid response element and an AP-1 motif, which mediated signal dependent activation
Torres et al., Cell Tissue Res 2007
:
Distribution of cells expressing Jun and
Fos proteins and synthesizing DNA in the adrenal cortex of hypophysectomized rats :
regulation by ACTH and
FGF2 ... The
effects of adrenocorticotropic hormone ( ACTH ) and
fibroblast growth factor 2 (FGF2) on
Fos and Jun protein expression were investigated, and DNA synthesis was assessed by using bromodeoxyuridine ( BrdU ) incorporation
Nakayama et al., J Oral Sci 2012
:
In ROS17/2.8 cells,
FGF2 and FSK each
increased the gene expression of
c-FOS ( 7.2-fold and 10.7-fold, respectively ) ... However,
FGF/FSK did not
induce c-FOS gene expression
Nowakowski et al., Ginekol Pol 2012
(Disease Models, Animal...) :
AP-1 is
induced by extracellular-signal regulated kinases ( ERK 1/2 ) through the activation of
basic fibroblast growth factor (bFGF)
Bolego et al., Br J Pharmacol 1997
:
4. Both alpha, beta-meATP and
bFGF rapidly and transiently
induced the nuclear accumulation of
Fos and Jun
Bilsland et al., J Neurosci Methods 1998
:
A sub-population of cortical neurons within the cultures express
Fos in
response to fibroblast growth factor-1 or
fibroblast growth factor-2 but no cells respond with Fos expression on treatment with insulin-like growth factor-1