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CREB3 — FOS
Text-mined interactions from Literome
Bruning et al., Proc Natl Acad Sci U S A 2000
:
Thus Rsk-2 is required for growth factor stimulated expression of
c-Fos and transcriptional activation of Elk-1 and the serum response factor, but not for
activation of
CREB or the mitogen activated protein kinase pathway in response to PDGF and IGF-1 stimulation
Jeon et al., Immunopharmacology 2000
:
Treatment of DEX to RAW 264.7 cells
induced a dose related inhibition of NF-kappaB/Rel and
AP-1 in chloramphenicol acetyltransferase activity, while neither NF-IL6 nor
CREB/ATF activation was affected by DEX
Shimohata et al., J Neurochem 2005
(Neurodegenerative Diseases) :
The phosphorylation of
cAMP-responsive element binding protein ( CREB ) and
induction of
c-Fos in response to cAMP were strongly suppressed in Neuro2a cells expressing expanded polyglutamine
Forti et al., Mol Cell Biochem 2006
:
However, the cAMP derivatives db-cAMP and 8Br-cAMP, do not promote
CREB phosphorylation and
c-Fos induction in parental Balb3T3 and 3T3-AR transfectants, confirming previous report by others
Kim et al., Proc Natl Acad Sci U S A 2009
(Tetanus) :
In Drosophila motor neurons, induction of
AP-1 , a heterodimer of Fos and Jun,
induces cAMP- and
CREB dependent forms of presynaptic enhancement
Simpson et al., Neuroreport 1994
:
Although forskolin did not alter
CREB-IR , forskolin did
induce striatal P-CREB-IR and
Fos-IR by 2.5- and 10-fold, respectively
Collins-Hicok et al., Mol Cell Biol 1994
:
Both CRE binding protein ( CREB ) and activator protein 1 (AP-1) can regulate RD, but their effects are in opposite directions ;
CREB represses and AP-1 activates RD. CREB induced repression and
AP-1 activation require distinct elements within the control region, but their binding and functions overlap at CRE-3 ...
CREB repression
blocks AP-1 activation in unstimulated cells