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EPHB2 — VWF
Text-mined interactions from Literome
Song et al., Br J Haematol 2000
:
It is concluded that pVWF and thrombin induced JNK activation, but whereas thrombin
induced ERK2 activation
VWF did not ; functional ERK2 activity was also not required for pVWF- or thrombin dependent platelet activation
Mazharian et al., J Biol Chem 2005
(MAP Kinase Signaling System) :
The
ERK2 activity required for platelet adhesion was
dependent on the interaction of
vWF with GPIb
Garcia et al., Blood 2005
(MAP Kinase Signaling System) :
VWF induced
Erk2 phosphorylation and thromboxane A2 ( TXA2 ) release were completely blocked by PP2, an Src family kinase inhibitor, suggesting that Erk is downstream of Src family kinases