◀ Back to EPHB2
EPHB2 — EPS8
Text-mined interactions from Literome
Maa et al., Oncogene 2001
(Cell Transformation, Neoplastic...) :
Overexpression of p97Eps8 leads to cellular transformation : implication of pleckstrin homology domain in
p97Eps8 mediated
ERK activation
Robinet et al., FASEB J 2007
(Myocardial Reperfusion Injury) :
EPs interaction with S-Gal
triggered NO release and activation of PI3-kinase/Akt and
ERK1/2 in human coronary endothelial cells ( HCAECs ) and rat neonatal cardiomyocytes ( RCs )
Auciello et al., J Cell Sci 2013
:
Eps8 interacts with the clathrin mediated endocytosis machinery and depletion of Eps8
inhibits FGFR trafficking and immediate
Erk signalling