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EMD — EPHB2

Text-mined interactions from Literome

Itoh et al., J Periodontal Res 2006 : Our results indicate that EMD induces the formation of osteoclasts through interaction with RANKL, while ERK and p38 MAPK may play a critical role in the enhancement of osteoclast formation in RAW 264.7 cells
Zeldich et al., J Dent Res 2008 : Treatment of gingival fibroblasts with EMD resulted in tyrosine phosphorylation of the EGFR, as assessed by immunoblotting and ELISA, while EMD induced ERK activation and thymidine incorporation were markedly inhibited ( approximately 40-50 % ) by a specific EGFR tyrosine kinase inhibitor ... Taken together, these results indicate that, at least in human gingival fibroblasts, EMD induced ERK activation and proliferation are partially due to a Src dependent, metalloproteinase mediated transactivation of EGFR
Muchir et al., Biochim Biophys Acta 2009 (Cardiomyopathies...) : These results provide proof for the hypothesis that altered expression of emerin and A-type lamins activates ERK signaling, which in turn can cause cardiomyopathy
Sakoda et al., Eur J Oral Sci 2012 : Our results suggest that EMD stimulates VEGF production partially via TGF-ß1 and FGF-2 in human gingival fibroblasts and that EMD induced VEGF production is regulated by ERK , p38 MAPK, and PI3K/Akt pathways