Moriuchi et al., J Biol Chem 2003
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Here we report that the YY1 transcription factor down-regulates CCR5 promoter activity and that overexpression of YY1 reduces cell surface CCR5 expression and infectibility by R5-HIV-1
Lei et al., Biochem Biophys Res Commun 2005
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Finally, we conclude that the up-regulation of CCR5 and CXCR4 can at least partially contribute to the down-regulation of transfactor YY1 which is p38 MAPK pathway dependent and this up-regulation has little relationship with MTB and HIV co-infection