Gene interactions and pathways from curated databases and text-mining

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CA2 — STAR

Text-mined interactions from Literome

Manna et al., Endocrinology 1999 (Leydig Cell Tumor...) : The potentiating effect of Ca2+ on the hCG stimulated StAR response correlated with the acute progesterone ( P ) response ... The Ca2+ effect on hCG induced StAR mRNA expression was dramatically suppressed by 10 micromol/liter verapamil, a Ca2+ channel blocker
Spät et al., Mol Cell Endocrinol 2004 (Calcium Signaling) : Potassium induced cytoplasmic Ca2+ signal activates adenylyl cyclase ; induces and activates StAR , the protein that carries cholesterol to the inner mitochondrial membrane and also enhances the expression of aldosterone synthase
Cherradi et al., Mol Endocrinol 1998 : Similarly, while Ca2+ induced a marked accumulation of StAR protein in mitochondria of glomerulosa cells to 218 +/- 44 % ( n = 3 ) of controls, the presence of ANP led to a blockade of StAR protein mitochondrial import ( 113.3 +/- 15.0 % ) ... Nuclear run-on analysis showed that increases in intracellular Ca2+ resulted in transcriptional induction of the StAR gene and that ANP inhibited this process