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PTHLH — RAC1

Text-mined interactions from Literome

Aklilu et al., Cancer Res 2000 (Neoplasms, Experimental) : Moreover, a dominant negative Rac ( Rac N17 ) blocked serum induced PTHRP gene expression
Mula et al., Cancer Lett 2010 (Colonic Neoplasms...) : The positive effects of PTHrP on Rac1 activity and on cell migration and invasion are mediated via the guanine nucleotide exchange factor Tiam1 ... Knockdown of integrin a6ß4, which is upregulated by PTHrP, negates the PTHrP mediated increase in Rac1 activation ... Chemical inhibition of PI3-K negates the PTHrP mediated effects on Tiam1 and Rac1 activity