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Park et al., Carcinogenesis 2009
(Cell Transformation, Neoplastic...) :
Overexpression of phospholipase D enhances matrix metalloproteinase-2 expression and glioma cell invasion via protein kinase C and protein kinase A/NF-kappaB/Sp1 mediated signaling pathways ... In this study, we demonstrate that the increased expression of PLD and its enzymatic activity in the glioma stimulate the secretion and expression of matrix metalloproteinase (MMP)-2 and induce the invasiveness of glioma cells
Reich et al., Clin Exp Metastasis 1995
(Fibrosarcoma...) :
Role of phospholipase D in laminin induced production of gelatinase A ( MMP-2 ) in metastatic cells