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HDAC2 — MYLIP
Text-mined interactions from Literome
Saito et al., Oncogene 2009
(Stomach Neoplasms) :
Analyses of chromatin modification show that DNA demethylation and
HDAC inhibition at Alu repeats
activates silenced
miR-512-5p by RNA polymerase II
Zhang et al., Oncogene 2012
(Lymphoma, Non-Hodgkin) :
Here, we investigated mechanisms of
miR-15a/16-1 transcriptional
repression and its epigenetic regulation by c-Myc and
histone deacetylase (HDAC) in MCL
Sampath et al., Blood 2012
(Leukemia, Lymphocytic, Chronic, B-Cell) :
HDAC inhibition triggered the accumulation of the transcriptionally activating chromatin modification H3K4me2 and
restored the expression of
miR-15a , miR-16, and miR-29b in approximately 35 % of samples
Buurman et al., Gastroenterology 2012
(Carcinoma, Hepatocellular...) :
In cell lines, inhibition of
HDAC significantly
increased levels of
hsa-miR-449a
Zhang et al., Cancer Cell 2012
(Lymphoma, B-Cell) :
We investigated the transcriptional and epigenetic
repression of
miR-29 by MYC,
HDAC3 , and EZH2 in mantle cell lymphoma and other MYC associated lymphomas
Mims et al., Leukemia 2013
(Leukemia, Myeloid, Acute) :
Thus,
HDAC inhibition may
increase miR-29b expression
Shi et al., Biochem Biophys Res Commun 2013
:
Synergistic
induction of
miR-126 by hypoxia and
HDAC inhibitors in cardiac myocytes ... Here we provide the first evidence that hypoxia and
HDAC inhibitors selectively and synergistically
stimulate expression of
miR-126 in cardiac myocytes
Li et al., Blood 2013
(Leukemia, Myeloid, Acute) :
Suppression of miR-193a expands the oncogenic activity of the fusion protein AML-ETO, because
miR-193a represses the expression of multiple target genes, such as AML1/ETO, DNMT3a,
HDAC3 , KIT, CCND1, and MDM2 directly, and increases PTEN indirectly
Noh et al., Cancer Lett 2013
(Carcinoma, Hepatocellular...) :
In conclusion, we suggest that loss or suppression of
miR-145 may
cause aberrant overexpression of
HDAC2 and promote HCC tumorigenesis
Lodrini et al., Nucleic Acids Res 2013
(Neuroblastoma) :
In profiling studies,
histone deacetylase (HDAC) inhibitor treatment most strongly
induced miR-183 ... In profiling studies,
histone deacetylase (HDAC) inhibitor treatment most strongly
induced miR-183
Zhou et al., PloS one 2013
:
C. parvum infection suppressed transcription of the
mir-424-503 gene in a NF-kB- and
HDAC dependent manner