Gene interactions and pathways from curated databases and text-mining

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DNMT3A — MYLIP

Text-mined interactions from Literome

Takada et al., RNA 2009 : Potential role of miR-29b in modulation of Dnmt3a and Dnmt3b expression in primordial germ cells of female mouse embryos ... Transcripts of the human genes for the de novo methyltransferases DNMT3A and DNMT3B have been identified as targets of miR-29b, and we found that mouse miR-29b also negatively regulates Dnmt3a and Dnmt3b expression in luciferase reporter assays
Bork et al., J Cell Physiol 2011 : Expression of the de novo DNA methyltransferases DNMT3A and DNMT3B was up-regulated by transfection of miR-371 whereas expression of DNMT3A was down-regulated by miR-369-5p
Chavali et al., Biochem Biophys Res Commun 2012 (Diabetes Mellitus...) : We tested the hypothesis that miR-133a regulates DNA methylation by inhibiting Dnmt-1 ( maintenance ) and Dnmt-3a and -3b ( de novo ) methyl transferases in diabetic hearts by using Ins2 ( +/- ) Akita ( diabetic ) and C57BL/6J ( WT ), mice and HL1 cardiomyocytes
Li et al., Blood 2013 (Leukemia, Myeloid, Acute) : Suppression of miR-193a expands the oncogenic activity of the fusion protein AML-ETO, because miR-193a represses the expression of multiple target genes, such as AML1/ETO, DNMT3a , HDAC3, KIT, CCND1, and MDM2 directly, and increases PTEN indirectly
Pandi et al., PloS one 2013 (Brain Infarction...) : Furthermore, treatment with REST siRNA prevented the post-ischemic miR-29c down-regulation and DNMT3a induction in PC12 cells and curtailed ischemic cell death ( by 64±9 % ; p < 0.05 ) compared to control siRNA treatment
Tan et al., Biochem Biophys Res Commun 2013 (Carcinoma, Non-Small-Cell Lung...) : The expression of miR-29a and miR-29b was partially regulated by DNMT3A and DNMT3B in a positive feedback loop